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Article

Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics.

Biology direct - 25 Jun 2012

Zhang Dapeng, de Souza Robson F, Anantharaman Vivek, Iyer Lakshminarayan M, Aravind L

Abstract excerpt

BACKGROUND: Proteinaceous toxins are observed across all levels of inter-organismal and intra-genomic conflicts. These include recently discovered prokaryotic polymorphic toxin systems implicated in intra-specific conflicts. They are characterized by a remarkable diversity of C-terminal toxin domains generated by recombination with standalone toxin-coding cassettes. Prior analysis revealed a striking diversity of...

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Identifiers

PMID: 22731697
DOI: 10.1186/1745-6150-7-18
PMCID: PMC3482391

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