Article

CD46 targeted <sup>212</sup> Pb alpha particle radioimmunotherapy for prostate cancer treatment

2022-10-18

Abstract excerpt

<h4>ABSTRACT</h4> We recently identified CD46 as a novel prostate cancer cell surface antigen that shows lineage independent expression in both adenocarcinoma and small cell neuroendocrine subtypes of metastatic castration resistant prostate cancer (mCRPC), discovered an internalizing human monoclonal antibody YS5 that binds to a tumor selective CD46 epitope, and developed a microtubule inhibitor-based antibody d...

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Literature Corpus work: e6f8fe7f-14b0-56a6-b0e0-461d7aa7ae85
DOI: 10.1101/2022.10.14.512321

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