Article

Development of an iPSC-derived resident tissue macrophage-based platform for the in vitro immunocompatibility assessment of human tissue engineered matrices

2024-03-07

Abstract excerpt

Upon implanting tissue-engineered heart valves (TEHVs), blood-derived macrophages are believed to orchestrate the remodeling process. They initiate the immune response and mediate the remodeling of the TEHV, essential for the valve's functionality. The exact role of another macrophage type, the resident tissue macrophages (RTMs), has not been yet elucidated even though they maintain the homeostasis of native tissu...

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Literature Corpus work: f3f560eb-44bb-5066-9756-c1d7337cfa41
DOI: 10.21203/rs.3.rs-3929294/v1

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