Article

SYS-Mut: Decoding the Functional Significance of Rare Somatic Mutations in Cancer

2021-09-06

Abstract excerpt

Current tailored-therapy efforts in cancer are largely focused on a small number of highly recurrently-mutated driver genes but therapeutic targeting of these oncogenes remains challenging. On the other hand, the vast number of genes mutated infrequently across cancers have received less attention, in part, due to a lack of understanding of their biologic significance. Here we present SYS-Mut, a systems biology pl...

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Literature Corpus work: f3dd8529-32ea-5af9-9017-24990bb8af2f
DOI: 10.1101/2021.09.03.458896

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