Article

Targeting Microglia Via Nanotechnology: A Novel Strategy to Overcome Neuroinflammation in Major Depressive Disorder

2025-07-28

Abstract excerpt

Major Depressive Disorder (MDD) is a highly prevalent psychiatric condition characterized by complex neurobiological mechanisms, including oxidative stress and neuroinflammation, with microglial activation playing a key role in its pathophysiology. Conventional antidepressants, though widely used, often fail to achieve remission due to limited efficacy, adverse effects, and poor patient adherence. In this context,...

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Literature Corpus work: f3c8ba74-e3ff-5676-9ffe-4a9b82611881
DOI: 10.20944/preprints202507.2222.v1

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