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Article

PiRNA-46545 Is a Potential Modulator of Lung Tumor Microenvironment and Drug Resistance

2026-05-25

Abstract excerpt

RASSF1C modulates expression of PIWI-(Drosophila)-like 1 (PIWIL1), as well as novel PIWI-interacting RNAs (piRNAs), which are regulators of the stem cell phenotype linked to development of lung oncogenesis, in part, through modulation of tumor microenvironment. We reported in previous work that restoring piR-46545 inhibits colony formation and migration/invasion of lung cancer cells overexpressing RASSF1C or PIWIL...

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Literature Corpus work
f3a9cde8-fb7c-5729-b4d3-557112b54bdc
DOI
10.20944/preprints202605.1632.v1
Open publication

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