Article

PiRNA-Hsap_1847317 may serve as a novel biomarker of PD-1 inhibitor resistance in patients with advanced non-small cell lung cancer

2025-09-30

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Resistance to PD-1 inhibitors poses a major challenge in treating NSCLC. This study explores the epigenetic mechanisms of PD-1 inhibitor resistance, focusing on piRNA expression and related signaling pathways. <bold>Methods</bold> : High-throughput sequencing was performed on blood samples from three NSCLC patient pairs before and after PD-1 inhibitor resi...

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Literature Corpus work: d80a2276-6947-5781-babb-22e2ca228670
DOI: 10.21203/rs.3.rs-7659429/v1

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