Article

Signaling scaffold Shoc2 regulates lymphangiogenesis by suppressing mTORC1-mediated IFN responses

2025-03-29

Abstract excerpt

<h4>ABSTRACT</h4> An interplay of growth factors and signaling pathways governs the development and maintenance of the lymphatic vasculature, ensuring proper fluid homeostasis and immune function. Disruption of these regulatory mechanisms can lead to congenital lymphatic disorders and contribute to various pathological conditions. However, the mechanisms underlying the molecular regulation of these processes rema...

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Literature Corpus work: f37de3a4-1abb-5839-9524-781e5c472471
DOI: 10.1101/2025.03.26.645567

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