Article

HN1 Promotes Proliferation, Metastasis and Attenuates the Chemosensitivity of HCC Cells to Oxaliplatin by Inhibiting Degradation of HMGB1 Through Interacting With TRIM28

2021-08-03

Abstract excerpt

<h4>Background: </h4> The oxaliplatin-based chemotherapy has revealed an encouraging therapeutic efficacy for advanced hepatocellular carcinoma patients. However, the development of resistance limits its clinical utilization. In addition, the chemotherapy resistance in HCC is usually accompanied with other malignant phenotypes, such as cell proliferation and metastasis, which together result in poor prognosis of H...

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Literature Corpus work: f368e48b-1598-5f38-91ed-77264b7f8ad9
DOI: 10.21203/rs.3.rs-754224/v1

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