Article

RBCK1 promotes the stabilization of HBx by linear ubiquitination to drive the progression of HBV-associated hepatocellular carcinoma

2023-01-18

Abstract excerpt

<h4>Background: </h4> & Aims: Linear ubiquitin chain assembly complex (LUBAC) has been reported to participate in cancer progression, but its role in hepatocellular carcinoma (HCC) remains unknown. This study aimed to investigate the functions and potential tumorigenic mechanisms of LUBAC components in HBV-associated HCC. <h4>Methods: </h4>: The expression of LUBAC components ( RBCK1 , RNF31 , and Sharpin ) an...

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Literature Corpus work: 4d55271f-db80-5821-9201-f2a70ab29b15
DOI: 10.22541/au.167407899.94032949/v1

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