Article

C-ToMExO: Learning Cancer Progression Dynamics from Clonal Composition of Tumors

2022-12-23

Abstract excerpt

Cancer is an evolutionary process involving the accumulation of somatic mutations in the genome. The tumor’s evolution is known to be highly influenced by specific somatic mutations in so-called cancer driver genes. Cancer progression models are computational tools used to infer the interactions among cancer driver genes by analyzing the pattern of absence/presence of mutations in different tumors of a cohort. In...

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Literature Corpus work: f349fbe4-7602-54a7-ad8f-112bad52b054
DOI: 10.1101/2022.12.23.521788

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