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3d Pharamacophore Model, Virtual Screening, Binding Affinity and Molecular Dynamics Studies of Potential Anticancerous Compounds Against Mammalian Target Rapamycin

2023-07-10

Abstract excerpt

<title>Abstract</title> <p>Breast cancer is a genetically-based public health issue that affects people worldwide. The advancement of the FKBP12-rapamycin complex of the mammalian target (mTOR), the protein that is dysregulated in breast cancer, is essentially concerned with a hormone receptor. The mTORC1 and mTORC2 multiprotein complexes may be cleaved by mTOR, a serine/threonine kinase. mTOR's fap receptor move...

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Literature Corpus work
f33cc0f2-1fe5-55de-b527-005b569ac552
DOI
10.21203/rs.3.rs-3100361/v1
Open publication

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3d Pharamacophore Model, Virtual Screening, Binding Affinity and Molecular Dynamics Studies of Potential Anticancerous Compounds Against Mammalian Target RapamycinDOI 10.21203/rs.3.rs-3100361/v1
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