Article
Natural Compounds or Their Derivatives against Breast Cancer: A Computational Study.
BioMed research international - 1 Jan 2022
Hossain Rajib, Ray Pranta, Sarkar Chandan, Islam Md Shahazul, Khan Rasel Ahmed, Khalipha Abul Bashar Ripon, Islam Muhammad Torequl, Cho William C, Martorell Miquel, Sharifi-Rad Javad, Butnariu Monica, Umbetova Almagul, Calina Daniela
Abstract excerpt
Background: Breast cancer is one of the most common types of cancer diagnosed and the second leading cause of death among women. Breast cancer susceptibility proteins of type 1 and 2 are human tumor suppressor genes. Genetic variations/mutations in these two genes lead to overexpression of human breast tumor suppressor genes (e.g., BRCA1, BRCA2), which triggers uncontrolled duplication of cells in humans. In...
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