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Nanocell COVID-19 vaccine elicits iNKT-licensed dendritic cells to produce high affinity antibodies neutralizing Variants of Concern

2022-04-07

Abstract excerpt

<title>Abstract</title> <p>For COVID-19 vaccines, high-affinity antigen-specific antibody, CD8+ T cell and memory B cell responses are essential to maximize protection against Variants of Concern (VOC). We report results in vitro, in mice and human volunteers immunized with bacterially-derived, non-living nanocells (EDVTM) packaged with bacterial plasmid expressing spike protein of SARS-CoV-2 and IFNγ stimulating...

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Literature Corpus work
f33c07a5-b29b-58d5-9e35-b1e221de77da
DOI
10.21203/rs.3.rs-1472661/v1
Open publication

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Nanocell COVID-19 vaccine elicits iNKT-licensed dendritic cells to produce high affinity antibodies neutralizing Variants of ConcernDOI 10.21203/rs.3.rs-1472661/v1
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