Article

Studies on cyclic AMP phosphodiesterases

1997-01-01

Abstract excerpt

The second messenger cyclic AMP plays a pivotal role in the control of cell function through the transduction of extracellular signals into intracellular activation. However, this cyclic nucleotide negatively modulates the synthesis and release of inflammatory mediators and the proliferation of lymphocytes. The sole mechanism for degradation of cAMP is achieved through the action of cyclic AMP phosphodiesterses (P...

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Literature Corpus work: f2a9baab-8e54-5198-8cbc-3b78bb4dabaf
DOI: 10.5525/gla.thesis.71726

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