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A quantitative method for determination of colistin E2 methane sulphonate sodium (CMS E2) in human plasma by 15N-labeled colistin E2

2023-05-03

Abstract excerpt

The single-component colistin E2, with superior antibacterial activity and lower toxicity, was being developed as the latest generation of polymyxin drugs. However, colistin E2 has not been tested quantitatively in biological matrices. In this study, based on the quantitative detection of CMS and colistin by Zhao et al., 15 N-labeled colistin E2 was used as an internal standard (IS) for a more accurate quantitativ...

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Literature Corpus work
f29f3329-c4ea-562c-8f0c-8a1e050261bc
DOI
10.21203/rs.3.rs-2830640/v1
Open publication

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A quantitative method for determination of colistin E2 methane sulphonate sodium (CMS E2) in human plasma by 15N-labeled colistin E2DOI 10.21203/rs.3.rs-2830640/v1
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