Article

Single cell-derived spheroids for real-time growth and metabolomic studies in breast cancer

2025-03-01

Abstract excerpt

Breast cancer remains a leading cause of cancer-related mortality, with disease progression and metastasis posing significant challenges in treatment. Three-dimensional (3D) cancer models have emerged as valuable tools for studying cancer cell biology in a physiologically relevant microenvironment. Studying the tumour heterogeneity and metabolic adaptations at the single-cell level can be crucial to identify facto...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f1e02bfb-8afb-5dd8-87ea-501a35009bd5
DOI: 10.1101/2025.02.28.638104

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single cell-derived spheroids for real-time growth and metabolomic studies in breast cancerDOI 10.1101/2025.02.28.638104Read

Enhanced characterization of breast cancer phenotypes using Raman micro-spectroscopy on stainless steel substrate.Semantic proximity Read

Towards optimized breast cancer 3D spheroid mono- and co-culture models for pharmacological research and screeningSemantic proximity Read

High-Throughput 3D Bioprinted Organoids of Skin Cancer Utilized for Diagnosis and Personalized TherapySemantic proximity Read

Combined SERS-Raman screening of HER2-overexpressing or silenced breast cancer cell linesSemantic proximity Read

Patient-derived tumor spheroid cultures as a promising tool to assist personalized therapeutic decisions in breast cancerSemantic proximity Read

The Use of Patient-Derived Organoids in the Study of Molecular Metabolic Adaptation in Breast CancerSemantic proximity Read

Adipocytes reprogram the proteome of breast cancer cells in organotypic three-dimensional cell culturesSemantic proximity Read

Tunable synthetic extracellular matrices to investigate breast cancer response to biophysical and biochemical cuesSemantic proximity Read

An optimised patient-derived explant platform for breast cancer reflects clinical responses to chemotherapy and antibody-directed therapySemantic proximity Read

A Multimodal Imaging Framework to Advance Phenotyping of Living Label-free Breast Cancer Cells.Semantic proximity Read

Integration of molecular profiling and chemical imaging to elucidate fibroblast-microenvironment impact on cancer cell phenotype and endocrine resistance in breast cancer.Semantic proximity Read

Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes.Semantic proximity Read