Article

Adaptive epigenetic regulation of neuronal metabolism by a mitochondrial redox signal

2023-12-10

Abstract excerpt

Different signaling pathways connect the mitochondrion with the transcriptional machinery in the nucleus. Redox events are thought to play a substantial role along this axis, however, many open questions about their specificity, quantitative importance and mode of action remain. Here, we have employed subtoxic doses of the complex I inhibitor MPP + in human neuronal LUHMES cells to characterize the contribution o...

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Literature Corpus work: f18f3f1e-fd09-52f2-b3c0-5a98889543a7
DOI: 10.1101/2023.12.10.570533

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