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Article

Untangling the Complexity of Childhood Atopic Dermatitis: Phenotypes and Endotypes.

Clinical reviews in allergy & immunology - 2 Mar 2026

Dumycz Karolina, Zygadło Joanna, Marzec Aleksandra, Strus Piotr, Kulus Marek, Sokolowska Milena, Venter Carina, Leung Donald Y M, Feleszko Wojciech

Abstract excerpt

Atopic dermatitis (AD) is a highly prevalent, chronic inflammatory skin disease that predominantly begins in early childhood. Increasing evidence supports that pediatric AD is not a single entity, but rather a spectrum of overlapping phenotypes and endotypes, defined by clinical presentation, immune profile, genetics, ethnicity, and comorbid atopic conditions. This review provides a comprehensive synthesis of...

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PMID: 41770295
DOI: 10.1007/s12016-025-09128-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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