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Single‐cell RNA ‐seq reveals abnormal differentiation of keratinocytes and increased inflammatory differentiated keratinocytes in atopic dermatitis

16 Jun 2023

Abstract excerpt

Abstract Background Atopic dermatitis (AD) is a chronic and recurrent inflammatory skin disease characterized by severe pruritus and eczematous lesions. Heterogeneity of AD has been reported among different racial groups according to clinical, molecular and genetic differences. Objective This study aimed to conduct an in‐depth transcriptome analysis of AD in Chinese population. Methods We performed single‐cell...

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PMID: 37326015
DOI: 10.1111/jdv.19256

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