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The Nef protein of the macrophage tropic HIV-1 strain AD8 counteracts human Bst-2/tetherin

2020-02-07

Abstract excerpt

Bst-2/tetherin inhibits the release of numerous enveloped viruses by physically attaching nascent particles to infected cells during the process of viral budding from the cell surface. Tetherin also restricts human immunodeficiency viruses (HIV), and pandemic main (M) group HIV-1s are thought to exclusively rely on their Vpu proteins to overcome tetherin-mediated restriction of virus release. However, at least one...

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Literature Corpus work
f15a1ce6-3ce0-5017-880b-d91740ee9632
DOI
10.1101/2020.02.07.938464
Open publication

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The Nef protein of the macrophage tropic HIV-1 strain AD8 counteracts human Bst-2/tetherinDOI 10.1101/2020.02.07.938464
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