Article

Intestinal myofibroblasts regulate intestinal epithelial cell plasticity via YAP/TAZ

2022-10-10

Abstract excerpt

<h4>ABSTRACT</h4> Intestinal stromal cells play a key role as the crypt niche cells during epithelial homeostasis and tumor initiation. However, the underlying cellular and molecular mechanisms remain unclear. We developed various types of three-dimensional (3D) tissue culture models to culture small intestinal myofibroblasts (SI MFs) together with enteroids. SI MFs significantly enhanced self-renewal, lumen form...

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Literature Corpus work: f140c87f-21eb-5f0a-961b-b7b4b993f8bf
DOI: 10.1101/2022.10.07.511327

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