Article

Group 3 Innate Lymphoid Cells are regulated by WASP in a microbiota-dependent manner

2022-07-20

Abstract excerpt

Wiskott-Aldrich syndrome protein (WASP) is a cytoskeletal regulator that is largely restricted to hematopoietic cells. While WASP expression in both lymphocytes and macrophages play a critical role in maintaining intestinal homeostasis, the function of WASP in innate lymphoid cells is unknown. Here we analyzed the role of WASP in the differentiation and function of group 3 innate lymphoid cells (ILC3s). WASP-defic...

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Literature Corpus work: f05c7a6e-335e-5b9a-a20d-b60e68ab23b6
DOI: 10.1101/2022.07.19.500438

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