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Integrated single-cell and bulk transcriptomic analysis leverages liver metastasis-related genes to develop a prognostic model for colorectal cancer patients

2026-03-30

Abstract excerpt

<h4>Purpose</h4> Differentially expressed genes (DEGs) between colorectal cancer liver metastasis (CRLM) epithelium and primary colorectal cancer (CRC) epithelium (LMR DEGs) identified based on single-cell RNA sequencing (scRNA-seq) data may become new biomarkers for CRC prognosis. <h4>Methods</h4> An scRNA-seq dataset was used to describe the cellular landscape of primary CRC and CRLM and identify LMR DEGs. Pro...

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Literature Corpus work
f00bf9cc-d103-56de-afc0-adb5f9704c84
DOI
10.64898/2026.03.24.714024
Open publication

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Integrated single-cell and bulk transcriptomic analysis leverages liver metastasis-related genes to develop a prognostic model for colorectal cancer patientsDOI 10.64898/2026.03.24.714024
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