Article

RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon

2020-01-23

Abstract excerpt

Broad dysregulation of gene expression control is a hallmark of cancer progression. Identifying the underlying master regulators that drive pathological gene expression is a key challenge in precision oncology. Here, we have developed a network analytical framework, named PRADA, that identifies oncogenic RNA-binding proteins through the systematic detection of coordinated changes in their target regulons. Applicat...

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Literature Corpus work: f0073408-4aa6-5eaa-80c6-23aa69e31b2f
DOI: 10.1101/2020.01.22.916205

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