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Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression

1 May 2020

Abstract excerpt

Colorectal cancer (CRC) is the most common gastrointestinal malignancy in the U.S.A. and approximately 50% of patients develop metastatic disease (mCRC). Despite our understanding of long non-coding RNAs (lncRNAs) in primary colon cancer, their role in mCRC and treatment resistance remains poorly characterized. Therefore, through transcriptome sequencing of normal, primary, and distant mCRC tissues we find 148...

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PMID: 32358485
DOI: 10.1038/s41467-020-15547-8

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