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Article

LncRNA CRLM1 inhibits apoptosis and promotes metastasis through transcriptional regulation cooperated with hnRNPK in colorectal cancer

30 Jul 2022

Abstract excerpt

BACKGROUND: Colorectal liver metastases (CRLM) continue to have a low survival rate. The number of CRLM regulators and clinical indicators remains limited. Long non-coding RNAs (lncRNAs) are a new master regulator of cell invasion and metastasis. However, the function and regulation mechanism of lncRNAs in colorectal cancer (CRC) metastasis are yet unknown. METHODS: To screen and identify CRLM-related lncRNAs,...

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PMID: 35907898
DOI: 10.1186/s13578-022-00849-9

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