Article

<i>Arid1a</i> protects against hepatic steatosis and insulin resistance via PPARα-mediated fatty acid oxidation

2019-01-09

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) have become a worldwide health concern because of lifestyle changes, but it is still lack of specific therapeutic strategies as the underlying molecular mechanisms remain poorly understood. Our previous study indicated that deficiency of Arid1a , a key component of SWI/SNF chromatin remodeling complex, initiated mouse steatohepatitis, implying t...

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Literature Corpus work: eff7505a-07fa-589f-8ea8-472ef9b9156e
DOI: 10.1101/507517

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