Article

Increased activation of the WNT pathway in brain tissue from patients with cortical dysplasia type IIb: genetics and functional aspects

2024-10-23

Abstract excerpt

<title>Abstract</title> <p>Focal Cortical Dysplasia (FCD) is a malformation of cortical development characterized by a heterogeneous group of lesions with high epileptogenic activity. The origin of FCD may be related to neuronal proliferation and differentiation, with the Wnt/β-catenin pathway being one of the main factors responsible for mediating these processes. Residual samples were obtained from the neocorte...

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Literature Corpus work: efd7e4ed-34ce-558a-a98c-b29bf613a50e
DOI: 10.21203/rs.3.rs-5199690/v1

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