Article

Lithium ameliorates Cornelia de Lange syndrome associated phenotypes in experimental models

2020-07-15

Abstract excerpt

<h4>ABSTRACT</h4> Cornelia de Lange Syndrome (CdLS) is a rare developmental disorder affecting a multitude of organs including the central nervous system, inducing a variable neurodevelopmental delay. CdLS malformations derive from deregulation of developmental pathways, inclusive of the canonical WNT pathway. We have evaluated MRI anomalies and behavioral and neurological clinical manifestations in CdLS patients...

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Literature Corpus work: aba69926-e04e-5dea-8883-ec845e92166e
DOI: 10.1101/2020.07.15.204628

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