Article

Two-variable nullcline analysis of ionic general equilibrium predicts calcium homeostasis in ventricular myocytes

2019-12-02

Abstract excerpt

Ventricular contraction is roughly proportional to the amount of calcium released from the Sarcoplasmic Reticulum (SR) during systole. While it is rather straightforward to measure calcium levels and contractibility under different physiological condition, the complexity of calcium handling during systole and diastole has made the prediction of its release at steady state impossible. Here we approach the problem a...

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Literature Corpus work: efcdb3c9-1d14-572c-ba36-492ce84b577a
DOI: 10.1101/861997

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