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pTripleTREP – A vector for tightly controlled expression and purification of virulence factors in Staphylococcus aureus

20 May 2025

Abstract excerpt

Abstract Background Recombinant proteins facilitate and contribute to detailed studies of the virulence mechanisms and pathophysiology of the major human pathogen Staphylococcus aureus. Of particular interest are secreted virulence factors. However, due to their potential toxicity and specific post-translational processing, virulence factors are difficult targets for heterologous protein production. Purified...

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PMID: 40394585
DOI: 10.1186/s12934-025-02736-7

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