Article

Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair

2020-04-07

Abstract excerpt

Cells are exposed to frequent mechanical and/or chemical stressors that can compromise the integrity of the plasma membrane and underlying cortical cytoskeleton. The molecular mechanisms driving the immediate repair response launched to restore the cell cortex and circumvent cell death are largely unknown. Using microarrays and drug-inhibition studies to assess gene expression, we find that initiation of cell woun...

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Literature Corpus work: efbd5299-ee19-55de-b377-6767a76f9d08
DOI: 10.1101/2020.04.06.028662

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