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Article

Retention and loss of RNA interference pathways in trypanosomatid protozoans.

PLoS pathogens - 28 Oct 2010

Lye Lon-Fye, Owens Katherine, Shi Huafang, Murta Silvane M F, Vieira Ana Carolina, Turco Salvatore J, Tschudi Christian, Ullu Elisabetta, Beverley Stephen M

Abstract excerpt

RNA interference (RNAi) pathways are widespread in metaozoans but the genes required show variable occurrence or activity in eukaryotic microbes, including many pathogens. While some Leishmania lack RNAi activity and Argonaute or Dicer genes, we show that Leishmania braziliensis and other species within the Leishmania subgenus Viannia elaborate active RNAi machinery. Strong attenuation of expression from a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21060810
DOI: 10.1371/journal.ppat.1001161
PMCID: PMC2965760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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