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Article

Activation of Nrf2 Pathway by 4-Octyl Itaconate Enhances Donor Lung Function in Cold Preservation Settings

2024-08-14

Abstract excerpt

<title>Abstract</title> <p><italic><bold>Background</bold></italic>: Lung transplantation is the primary treatment for end-stage lung diseases. However, ischemia-reperfusion injury (IRI) significantly impacts transplant outcomes. 4-Octyl itaconate (4-OI) has shown potential in mitigating organ IRI, although its effects in lung transplantation require further exploration. <italic><bold>Methods</bold></italic>: BEA...

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Literature Corpus work
ef970457-d85e-505e-917f-761c60f6c3d7
DOI
10.21203/rs.3.rs-4787494/v1
Open publication

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Activation of Nrf2 Pathway by 4-Octyl Itaconate Enhances Donor Lung Function in Cold Preservation SettingsDOI 10.21203/rs.3.rs-4787494/v1
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