Article
Ischemia-Reperfusion Injury in a Simulated Lung Transplant Setting Differentially Regulates Transcriptomic Profiles between Human Lung Endothelial and Epithelial Cells.
Cells - 10 Oct 2021
Saren Gaowa, Wong Aaron, Lu Yun-Bi, Baciu Cristina, Zhou Wenyong, Zamel Ricardo, Soltanieh Sahar, Sugihara Junichi, Liu Mingyao
Abstract excerpt
Current understanding of mechanisms of ischemia-reperfusion-induced lung injury during lung preservation and transplantation is mainly based on clinical observations and animal studies. Herein, we used cell and systems biology approaches to explore these mechanisms at transcriptomics levels, especially by focusing on the differences between human lung endothelial and epithelial cells, which are crucial for...
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