Article

Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques

2021-09-08

Abstract excerpt

Advanced age is a key predictor of severe COVID-19. To gain insight into this relationship, particularly with respect to immune responses, we utilized the rhesus macaque model of SARS-CoV-2 infection. Two cohorts of eight older (16-23 years) and eight younger (3-5 years) rhesus macaques were inoculated with SARS-CoV-2. Animals were evaluated using viral RNA quantification, clinical observations, thoracic radiograp...

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Literature Corpus work: ef81dc35-5e41-5847-9fe2-48cfb1055c1e
DOI: 10.1101/2021.09.08.459430

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