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Analysis of UK Biobank Cohort Reveals Novel Insights for Thoracic and Abdominal Aortic Aneurysms

2021-02-05

Abstract excerpt

<h4>Background</h4> Thoracic aortic aneurysm (TAA) and abdominal aortic aneurysm (AAA) are known to have a strong genetic component. <h4>Methods and Results</h4> In a genome-wide association study (GWAS) using the UK Biobank, we analyzed the genomes of 1,363 individuals with AAA compared to 27,260 age, ancestry, and sex-matched controls (1:20 case:control study design). A similar analysis was repeated for 435 in...

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Literature Corpus work: ef27a1c2-bdeb-5a46-8a5c-0a147e505238
DOI: 10.1101/2021.02.05.429911

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