Article

Leucoverdazyls as novel potent inhibitors of enterovirus replication

2024-04-11

Abstract excerpt

Enteroviruses (EV) are important pathogens causing human disease with various clinical manifestations. To date, treatment of enteroviral infections is mainly supportive since no vaccination or antiviral drugs are approved for their prevention or treatment. Here, we describe the antiviral properties and mechanisms of action of leucoverdazyls - novel heterocyclic compounds with antioxidant potential. The lead compou...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ef2742fc-d76c-5752-ab7d-7ce41c0316c9
DOI: 10.20944/preprints202404.0785.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Leucoverdazyls as novel potent inhibitors of enterovirus replicationDOI 10.20944/preprints202404.0785.v1Read

Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)Semantic proximity Read

Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal MutagenesisSemantic proximity Read

Combating enterovirus replication: State-of-the-art on antiviral researchSemantic proximity Read

Characterization of three small molecule inhibitors of enterovirus 71 identified from screening of a library of natural products.Semantic proximity Read

Inhibition of enterovirus 71 replication by an α-hydroxy-nitrile derivative NK-1.9k.Semantic proximity Read

Bioactive natural compounds against human coronaviruses: a review and perspectiveSemantic proximity Read

Review of Phytochemical Compounds as Antiviral Agents Against Arboviruses from the Genera Flavivirus and Alphavirus.Semantic proximity Read

Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acidSemantic proximity Read

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430Semantic proximity Read

Identification of dibucaine derivatives as novel potent enterovirus 2C helicase inhibitors: In vitro, in vivo, and combination therapy studySemantic proximity Read

Selective human enterovirus and rhinovirus inhibitors: An overview of capsid‐binding and protease‐inhibiting moleculesSemantic proximity Read

Conserved Residues Adjacent to ß-Barrel and Loop Intersection among Enterovirus VP1 Affect Viral Replication: Potential Target for Anti-Enteroviral Development.Semantic proximity Read