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Conserved Residues Adjacent to ß-Barrel and Loop Intersection among Enterovirus VP1 Affect Viral Replication: Potential Target for Anti-Enteroviral Development.

Viruses - 10 Feb 2022

Huang Ya-Ling, Huang Sheng-Wen, Shen Chun-Yu, Cheng Dayna, Wang Jen-Ren

Abstract excerpt

Enterovirus genus has over one hundred genotypes and could cause several kinds of severe animal and human diseases. Understanding the role of conserved residues in the VP1 capsid protein among the enterovirus genus may lead to anti-enteroviral drug development. The highly conserved residues were found to be located at the loop and ß-barrel intersections. To elucidate the role of these VP1 residues among the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35215957
DOI: 10.3390/v14020364
PMCID: PMC8877150

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