Article

A Scoring System to Evaluate the Impact of SNPs in a Path Related Context to Study Behçet’s Disease Aetiology in Japanese Population

2018-05-08

Abstract excerpt

<h4>Motivation</h4> Genome-wide association study (GWAS) is a powerful method that can provide a list of single nucleotide polymorphisms (SNPs) that are significantly related to the pathogenesis of a disease. Even though in Mendelian diseases strong associations can be found for certain SNPs, in most of the complex diseases only modest associations can be identified from the GWAS. Therefore, the main challenge in...

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Literature Corpus work: eeffa62c-b90e-5f3e-b8e0-ccc9da7ad19b
DOI: 10.1101/316562

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