Article
Genome-wide pathway analysis of a genome-wide association study on psoriasis and Behcet's disease.
Molecular biology reports - 1 May 2012
Lee Young Ho, Choi Sung Jae, Ji Jong Dae, Song Gwan Gyu
Abstract excerpt
The aim of this study was to identify candidate causal single nucleotide polymorphisms (SNPs) and candidate causal mechanisms of psoriasis and Behcets's disease (BD) and to generate an SNP → gene → pathway hypothesis. A psoriasis genome-wide association study (GWAS) dataset that included 436,192 SNPs in 1,409 psoriasis cases and 1,436 controls of European descent and a BD GWAS dataset that contained 310,324 SNPs...
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