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Melatonin Ameliorates High Fat Diet Induced Oxidative Stress-Mediated Insulin Resistance, Amyloid Burden and Memory Dysfunction in Female Mice and their offspring

2023-10-04

Abstract excerpt

High fat diet (HFD) is a prime factor, which contributes to the present epidemic of metabolic syndrome. HFD induces oxidative stress (OS) that in turn causes neuroinflammation, neurodegeneration, synaptic dysfunction, insulin resistance and amyloid burden. Pineal gland secretes a potent anti-apoptotic hormone, melatonin that has the potential to nullify the toxic effect of reactive oxygen species (ROS) and amelior...

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Literature Corpus work: eef3619a-45bd-5a5f-a56e-e3aafbbdbe17
DOI: 10.21203/rs.3.rs-3376865/v1

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