Article

ZEB2 signaling is essential for ureteral smooth muscle cell differentiation and maintenance

2025-02-25

Abstract excerpt

Mowat-Wilson Syndrome (MWS) is a multiple congenital anomaly syndrome caused by mutations in the ZEB2, which plays a critical role in cell fate determination and differentiation during development. Congenital anomalies of the kidney and urinary tract (CAKUT) have been reported in MWS patients. However, the role of ZEB2 in urinary tract development and the cellular and molecular mechanism underlining the CAKUT phe...

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Literature Corpus work: eebc7d99-1b97-5a72-a1fe-7e9e21beae4d
DOI: 10.1101/2025.02.23.639741

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