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Quantitative visualization of gene expression in <i>Pseudomonas aeruginosa</i> aggregates reveals peak expression of alginate in the hypoxic zone

2019-05-09

Abstract excerpt

It is well appreciated that oxygen- and nutrient-limiting gradients characterize microenvironments within chronic infections that foster bacterial tolerance to treatment and the immune response. However, determining how bacteria respond to these microenvironments has been limited by a lack of tools to study bacterial functions at the relevant spatial scales in situ . Here we report the application of the hybridiz...

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Literature Corpus work
ee6ff2b4-feb0-5e4f-9178-84085e2ea65a
DOI
10.1101/632893
Open publication

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