Article
AlgX Is a Periplasmic Protein Required for Alginate Biosynthesis in <i>Pseudomonas aeruginosa</i>
15 Oct 2004
Abstract excerpt
Alginate, an exopolysaccharide produced by Pseudomonas aeruginosa, provides the bacterium with a selective advantage that makes it difficult to eradicate from the lungs of cystic fibrosis (CF) patients. Previous studies identified a gene, algX, within the alginate biosynthetic gene cluster on the P. aeruginosa chromosome. By probing cell fractions with anti-AlgX antibodies in a Western blot, AlgX was localized...
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