FAM3 Cytokine-like Proteins, Their Putative Receptors and Signaling Pathways in Metabolic Diseases and Cancers

Abstract excerpt

FAM3A, FAM3B, FAM3C and FAM3D are members of “family with sequence similarity 3” (FAM3) gene family, an emerging class of cytokine-like proteins with a unique structural globular beta-beta-alpha fold and distinct biological functions. With widespread expression in tissue, organs and in many cell types, their specific roles in human diseases have been the focus of much research. FAM3A acts as a positive regulator o...

Topics

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• Autophagy
• Caspase 1
• Homeostasis
• Inflammatory Bowel Diseases
• Leukocytes, Mononuclear
• Monocytes
• Protein Tyrosine Phosphatases, Non-Receptor
• Toll-Like Receptors

Identifiers and source

Literature Corpus work

ee11b938-0f8c-58b9-8ddf-c089d3796b54

DOI

10.20944/preprints202601.0509.v1