Article

Etiological basis for chronic pain genetic variation in brain and dorsal root ganglia cell types

2025-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Chronic pain is a complex clinical problem comprising multiple conditions that may share a common genetic profile. Genome-wide association studies (GWAS) have identified many risk loci whose cell-type context remains unclear. Here, we integrated GWAS data on chronic pain ( N = 1,235,695) with single-cell RNA sequencing (scRNA-seq) data from human brain and dorsal root ganglia (hDRG), and single-...

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Literature Corpus work: 5f4add95-f0aa-5622-8d03-5062bfff3f73
DOI: 10.1101/2025.07.03.25330832

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