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Article

Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes.

Cell reports - 30 May 2017

Parisien Marc, Khoury Samar, Chabot-Doré Anne-Julie, Sotocinal Susana G, Slade Gary D, Smith Shad B, Fillingim Roger B, Ohrbach Richard, Greenspan Joel D, Maixner William, Mogil Jeffrey S, Belfer Inna, Diatchenko Luda

Abstract excerpt

Dorsal root ganglia (DRG) relay sensory information to the brain, giving rise to the perception of pain, disorders of which are prevalent and burdensome. Here, we mapped expression quantitative trait loci (eQTLs) in a collection of human DRGs. DRG eQTLs were enriched within untranslated regions of coding genes of low abundance, with some overlapping with other brain regions and blood cell cis-eQTLs. We confirm...

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Identifiers

PMID: 28564610
DOI: 10.1016/j.celrep.2017.05.018
PMCID: PMC5524461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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