Article

Single-cell RNA sequencing reveals CK19+ cancer stem cells and their specific SPP1+ tumor-associated macrophage niche in HBV-related hepatocellular carcinoma

2023-05-23

Abstract excerpt

<title>Abstract</title> <p>Purpose Cytokeratin 19-positive cancer stem cells (CK9 + CSCs) and their tumor-associated macrophages (TAMs) have not been fully explored yet in the hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). <bold>Experimental Design</bold>: Single-cell RNA sequencing was performed on the viable cells obtained from 11 treatment-naïve HBV-associated HCC patients, including 8 CK19 +...

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Literature Corpus work: edd3f6f6-c5fa-53b1-9f1d-43a2ed95cce0
DOI: 10.21203/rs.3.rs-2950088/v1

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